Call us today
Flexeril (cyclobenzaprine) is classified as a muscle relaxant. Flexeril is primarily used to relieve muscle spasms and pain associated with musculoskeletal conditions. It is not effective for relieving muscle spasms due to central nervous system disorders and diseases, such as multiple sclerosis, amyotrophic lateral sclerosis, or a brain or spinal cord injury. It is typically prescribed for acute back injuries and other forms of conditions where pain and muscle spasms are involved.
Flexeril’s primary action occurs in the brainstem, with some involvement occurring at the level of spinal cord. It also has several off-label uses; the most common off-label use for Flexeril is for the treatment of fibromyalgia pain and associated muscle spasms. Other off-label uses are listed as treatments for:
Flexeril is not listed by the United States Drug Enforcement Agency as a controlled substance; however, it can only be legally purchased with a doctor’s prescription and should be taken under the supervision of a doctor for treatment of a specific medical condition. Flexeril is typically used in conjunction with physical therapy or exercise and other forms of treatment for these conditions. Cyclobenzaprine is available in:
Cyclobenzaprine was synthesized in 1961 and is chemically related to a group of antidepressant medications known as the tricyclic antidepressants. It was found to have limited effects in treating depression and did not compare favorably to the available antidepressants at that time; however, it was noted that the drug did act as a central muscle relaxant.
Flexeril was approved by the FDA in 1977 for the treatment of acute muscle spasms. It is manufactured by Merck & Co. and marketed and distributed by McNeil Consumer & Specialty Pharmaceuticals.
Call now for FREE insurance and payment consultation
For the majority of patients using Flexeril, the recommended dosage appears to be 5 mg three times a day. Depending on the response of the individual, the dosage may be increased to 10 mg three times a day. For elderly patients and children, the dosages can be different. The use of Flexeril for periods longer than 2-3 weeks is not recommended. Typically, the medication is used for the short-term treatment of acute muscle spasms and muscle pain in conjunction with other forms of therapy. The evidence for its treatment utility indicates that beyond the 2-3 week window, it is not very effective in the treatment of muscle spasms.
Because Flexeril is structurally related to the tricyclic antidepressants, its hypothesized primary action is anticholinergic, meaning that it blocks the neurotransmitter epinephrine in the brain (at the same time strengthening the activity of norepinephrine).
The action of Flexeril is believed to work on two types of motor neurons in the brain and possibly spinal cord (alpha and gamma neurons) that are involved in the production of movement. Flexeril reduces the rate at which these neurons fire and therefore decreases the intensity and frequency of muscle spasms in people. It may also reduce pain that is associated with spasms, but pain reduction is not its primary treatment effect.
The onset of action (the time that it takes a drug to achieve its effects) is about 60 minutes. The half-life for Flexeril varies – it’s 8-37 hours for the immediate-release form, and 32-33 hours for the extended-release form. It remains in the system for a relatively long period, and this period may even be longer in young or elderly individuals.
There are several proposed advantages to using Flexeril to treat muscle spasms:
Some disadvantages include:
The most common side effects associated with Flexeril include:
Some of the less common side effects include:
In general, the potential for abuse and dependence with Flexeril is considered to be very low. However, individuals who abuse drugs are often very resourceful and it appears that most any medication can be abused. There is a potential for the development of withdrawal symptoms following an abrupt discontinuation of Flexeril use. Since the symptoms are relatively mild compared to other withdrawals, the symptoms associated with stopping Flexeril are often referred to as Flexeril discontinuation symptoms.
The common reported withdrawal symptoms include:
These symptoms rarely last for more than a few days. These withdrawal effects may not signify an addiction.
Flexeril use does not appear to produce physical dependence despite its potential to produce a mild withdrawal syndrome after prolonged use. However, there is a potential for a drug that produces sedation to be used in conjunction with other drugs and to be abused. Feelings of sedation and being relaxed are often interpreted by certain individuals as pleasurable even though they may not deliver the euphoria that other types of drugs deliver.
Flexeril abuse is well documented. For instance there was an 87 percent increase from the years 2004 to 2011 in the number of emergency room visits due to Flexeril abuse. Moreover, since the drug Soma was reclassified to a Schedule IV drug by the DEA, it appears that Flexeril abuse may have increased. Thus, abuse of Flexeril is a concern. Its street names include cycloneand mellow yellow.
The effects of Flexeril are enhanced when combined with other drugs, such as alcohol, benzodiazepines, and opiates. It appears as if at least some of the abuse of Flexeril occurs in this context. Moreover, the use of Flexeril beyond the 2-3 week timeframe for its therapeutic effects would also indicate abuse, as would buying Flexeril without a prescription or using it in a manner that it is not intended to be used.
There is a potential for psychological addiction to occur with prolonged abuse to Flexeril due to a couple of reasons:
Call now to speak to a consultant about your treatment options
A number of signs can point to a problem with Flexeril abuse or even a psychological addiction to the drug. Some general signs include:
Trying to point out someone’s dysfunctional behavior, particularly when it involves drug abuse, can be difficult. There are several concerns one should be aware of before approaching a friend or family member with this issue. The major concern one should have is that people with drug abuse issues will often not be very responsive and can even be abusive to others when attempting to discuss the issues with them. In fact, many individuals with drug abuse issues do not consider their use of the drug to be abusive.
There are several other major considerations and suggestions for approaching an individual and discussing abuse of drugs with them:
Depending on the situation, the person’s response, and the severity of the abuse issue, it may be more productive to schedule a formal intervention.
An intervention is a more formal discussion with an individual who has a problem that affects other people. Interventions recruit relatives and close friends to come together and point out these issues with the person of interest. One should not attempt to organize an intervention without guidance from a professional, such as an addiction counselor, interventionist, family mediator, physician, or other specialist. The professional can organize the intervention, keep it focused, and adjust the plan in order to make it a positive experience. Understand the following about an intervention:
Getting treatment for Flexeril abuse is not significantly different from substance abuse treatment in general. It is often useful to enroll the help of a physician in any substance abuse treatment program; however, it is not always necessary unless there are serious withdrawal symptoms associated with discontinuing the drug of choice. Since the discontinuation syndrome from stopping Flexeril is comparatively mild, it becomes a personal choice to include a physician to assist with discontinuing the drug. Medical detox is not generally necessary for Flexeril withdrawal, but medical professionals can help make the process more comfortable. If other drugs of abuse are also involved, medical detox may be necessary.
Typically, the person with the abuse problem will need to:
Although it is often considered to have a low potential for abuse, people do abuse Flexeril and such abuse can have serious consequences. People who receive understanding and support regarding their Flexeril abuse can be successful in making positive changes in their lives and getting off the drug.
You Can Start a New Life
Contact us today to talk with a Admission Navigator who will give you the information you need to make the right decision for you and your loved ones.