The withdrawal timeline for heroin will vary somewhat depending on a person’s history of heroin use, the doses regularly taken, and the person’s body composition. Generally, withdrawal begins 6-24 hours after last use of heroin, and symptoms continue for about a week, though they lessen as time passes.
What Is Heroin?
Heroin is an opioid drug synthesized from morphine. It usually appears as a white or brown powder, or a sticky black substance. This drug can be injected, inhaled, or smoked. All methods of administration deliver the drug to the brain very rapidly. Because of this, the substance is highly addictive and very damaging to the brain.
NIDA reports that 4.2 million Americans reported using heroin at least once in their lives in 2011, and 23 percent of people who use heroin become dependent on it. The average age of first use of heroin, according to SAMHSA, is 28 years old.
Effects of Heroin Use
Heroin is converted into morphine within the body. The morphine then binds to cells termed opioid receptors; these cells send a signal to the brain, which triggers the “high” associated with drug use. Repeated exposure to heroin changes brain structure and chemistry. These physical changes to the brain are why it can be so difficult to stop using heroin. Once a dependence on heroin has developed, stopping or reducing heroin use will lead to withdrawal symptoms.
Heroin use leads to dependence in many people. NIDA reports that dependence occurs when the body begins to rely on the drug to maintain normal functioning; lack of the drug in the system triggers withdrawal symptoms as the body attempts to readjust. After continued heroin use, greater amounts of the drug must be used to produce the same effects originally felt, which is termed drug tolerance. Different people become dependent on opiate drugs at different rates.
SAMHSA lists the symptoms of heroin use as:
- Depressed respiration
- Constricted pupils
An overdose of heroin can lead to the following:
- Shallow breathing
- Blue lips and fingernails
- Clammy skin
Withdrawal Symptoms and Timeline
Withdrawal occurs after stopping or significantly reducing the use of heroin. According to NIDA, withdrawal is the process by which the body rids itself of the drug. This can cause uncomfortable symptoms, both physical and psychological. While heroin withdrawal can be very unpleasant, it is not life-threatening.